Lethal effects of butylated hydroxytoluene (BHT) with hemorrhage

The peroxidase-dependent activation of butylated hydroxyanisole and butylated hydroxytoluene (BHT) to reactive intermediates. Formation of BHT-quinone methide via a chemical-chemical interaction.

The food antioxidants butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) are shown to be metabolized to covalent binding intermediates and various other metabolites by prostaglandin H synthase and horseradish peroxidase. BHA was extensively metabolized by horseradish peroxidase (80% conversion of parent BHA into metabolites) resulting in the formation of three dimeric products. O...

Effects of Butylated Hydroxytoluene on Freezability of Ram Spermatozoa

The present study was conducted to investigate the effects of butylated hydroxytoluene (BHT) supplementation on diluted, cooled and frozen-thawed ram spermatozoa. After primary evaluation of collected ejaculates, only semen samples with motility of more than 70% and sperm concentration higher than 3×10 sperm/ml were used for cryopreservation. The selected semen samples were then pooled and dilu...

Factorial Experimental Design Optimization of Solid Phase Microextraction (SPME) Conditions for Analysis of Butylated Hydroxytoluene (BHT) in Bottled Water

BHT é um antioxidante usado como aditivo em alguns alimentos e em plásticos de embalagens, e sua presença em água mineral engarrafada é possível devido à migração do aditivo contido nas paredes do recipiente. Planejamento fatorial foi empregado para determinar os valores ótimos para os parâmetros operacionais principais na análise de hidroxitolueno butilado (BHT) em água engarrafada usando micr...

Chemical intolerance to butylated-hydroxyanisole (BHA) and butylated-hydroxytoluene (BHT) and vascular response as an indicator and monitor of drug intolerance.

Hepatoprotective effect of food preservatives (butylated hydroxyanisole, butylated hydroxytoluene) on carbon tetrachloride-induced hepatotoxicity in rat

Carbon tetrachloride (CCl4), a hepatotoxic agent is widely used to study the toxic mechanisms in experimental animals. This study was carried out to establish the hepatoprotective measures of food preservative antioxidants butylated hydroxyanisole and butylated hydroxytolune (BHA, BHT) when mixed with food towards carbon tetrachloride (CCl4) intoxication (230 mg/ kg b wt/rat/day) in rat. Bioche...